Survival-associated meQTLs across different cancer types
We identified 23,432 meQTLs associated with patient overall survival across different cancer types at FDR < 0.05.
|
Cancer type
|
SNP ID
|
SNP position (hg19)
|
Alleles (A/a)
|
log-rank test p-value
|
Sample size
|
Median survival time AA
|
Median survival time Aa
|
Median survival time aa
|
|
|---|---|---|---|---|---|---|---|---|---|
| CRC | rs112322873 | chr12:59966614 | T/C | 1.19E-5 | 372 | 24.85 | 17.73 | 10.4 | KM Plot |
| CRC | rs112374479 | chr6:151711490 | T/C | 6.63E-5 | 373 | 22.83 | 20.5 | 12.97 | KM Plot |
| CRC | rs112460412 | chr6:53526863 | T/C | 2.75E-5 | 372 | 22.3 | 24.77 | 7.13 | KM Plot |
| CRC | rs113500769 | chr5:54575220 | A/AGACT | 4.95E-5 | 371 | 22.32 | 23.43 | 9.67 | KM Plot |
| CRC | rs114333320 | chr7:62014829 | G/A | 7.1E-7 | 359 | 22.75 | 20.05 | 11.27 | KM Plot |
| CRC | rs1151505 | chr11:65734539 | C/T | 4.88E-5 | 366 | 20.23 | 23.37 | 19.85 | KM Plot |
| CRC | rs115398540 | chr7:62132529 | A/T | 4.44E-6 | 368 | 24.33 | 20.08 | 14.37 | KM Plot |
| CRC | rs11543230 | chr1:16785564 | C/T | 1.06E-11 | 374 | 22.25 | 26.8 | 6.27 | KM Plot |
| CRC | rs11610531 | chr12:102032930 | G/A | 6.93E-9 | 369 | 22.2 | 26.33 | 5.1 | KM Plot |
| CRC | rs11665872 | chr19:56161898 | C/T | 2.35E-5 | 364 | 22.3 | 23.3 | 9.37 | KM Plot |
| CRC | rs11710223 | chr3:38676820 | T/A | 1.02E-6 | 367 | 21.87 | 30.23 | 14.73 | KM Plot |
| CRC | rs117610920 | chr12:59966586 | C/A | 1.19E-5 | 372 | 24.85 | 17.73 | 10.4 | KM Plot |
| CRC | rs11767784 | chr7:57728457 | C/G | 1.64E-6 | 374 | 11.92 | 20.3 | 23.37 | KM Plot |
| CRC | rs11769797 | chr7:156187901 | A/G | 5.31E-5 | 374 | 24.72 | 21.37 | 13.27 | KM Plot |
| CRC | rs11773551 | chr7:158136146 | C/T | 2.8E-6 | 358 | 21.9 | 25.13 | 14.87 | KM Plot |